X-Men – Reign of Apocalypse is a side-scrolling beat-’em-up for the Game Boy Advance, developed by Digital Eclipse and published by Activision. Players control Wolverine, Cyclops, Storm, or Rogue across 12 levels, fighting enemy waves and bosses in an alternate universe ruled by Apocalypse, with points earned to upgrade strength, vitality, or mutant power.
How To Play X-Men – Reign of Apocalypse
| Control | Action |
| D-Pad | Move character / navigate menus |
| A Button | Jump |
| B Button | Attack |
| L Button | Charge / special melee move (Wolverine, Rogue) |
| R Button | Projectile attack (Cyclops, Storm) |
| Start | Pause game |
About X-Men – Reign of Apocalypse
| Release Date | NA: September 26, 2001 | EU: October 5, 2001 |
| Developer | Digital Eclipse |
| Publisher | Activision |
| Platform | Game Boy Advance |
| Genre | Action / Beat-’em-up / 2D |
| Series | X-Men |
| Modes | Single-player, 2-player |
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